Solid phase strain promoted “click” modification of DNAvia[3+2]-nitrile oxide–cyclooctyne cycloadditions
نویسندگان
چکیده
منابع مشابه
Solid phase strain promoted "click" modification of DNA via [3+2]-nitrile oxide-cyclooctyne cycloadditions.
Rapid, catalyst free, solid phase modification of DNA by strain promoted cyclooctyne-nitrile oxide click chemistry is reported; the reaction is characterised by mild conditions, occurring in an aqueous environment under atmospheric conditions at room temperature and is complete in 10 minutes.
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ژورنال
عنوان ژورنال: Chem. Commun.
سال: 2011
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c0cc03985c